The purpose of this publication is to compare social and economic potential of neighbouring areas of: Poland (Lubelskie, Małopolskie, Podkarpackie and Śląskie voivodships), Slovakia (Banskobystricky, Kosický, Presovský and Zilinský regions) as well as Ukraine (L’viv, Volyn, Zakarpattia and Ivano-Frankivs’k regions). The publication highlights information concerning, among other things, demographic situation, environmental protection, labour market, entities of the national economy, gross domestic product, agriculture and tourism. Time period covers chiefly the years 2006 and 2007. Making comparisons is facilitated by indicators presented in the tabular part as well as by maps and graphs.